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The antibody against SF3A3 was raised in rabbit using the Human SF3A3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against SF3A3 was raised in rabbit using the Human SF3A3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
$600.00
| Cat.No | ADC-51907A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SF3A3 |
| Target Synonyms | SF3A3 antibody; SAP61 antibody; Splicing factor 3A subunit 3 antibody; SF3a60 antibody; Spliceosome-associated protein 61 antibody; SAP 61 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human SF3A3 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q12874 |
Uniprot Id
Q12874
Target Species
Human
Target Name
SF3A3
Target Full Name
Splicing factor 3A subunit 3
Target Function
Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes.
Target Subcellular Location
Nucleus speckle. Nucleus.
Target Protein Families
SF3A3 family
Target Tissue Specificity
Ubiquitous.
Target Synonyms
SF3A3; SAP61; Splicing factor 3A subunit 3; SF3a60; Spliceosome-associated protein 61; SAP 61
Target Background
This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.
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