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The antibody against SF3B5 was raised in rabbit using the Human SF3B5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.
The antibody against SF3B5 was raised in rabbit using the Human SF3B5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.
$600.00
| Cat.No | ADC-51905A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SF3B5 |
| Target Synonyms | SF3B5 antibody; SF3B10 antibody; Splicing factor 3B subunit 5 antibody; SF3b5 antibody; Pre-mRNA-splicing factor SF3b 10 kDa subunit antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, WB |
| Storage | Upon receipt |
| Immunogen Description | Human SF3B5 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BWJ5 |
Uniprot Id
Q9BWJ5
Target Species
Human
Target Name
SF3B5
Target Full Name
Splicing factor 3B subunit 5
Target Function
Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA.
Target Subcellular Location
Nucleus.
Target Protein Families
SF3B5 family
Target Synonyms
SF3B5; SF3B10; Splicing factor 3B subunit 5; SF3b5; Pre-mRNA-splicing factor SF3b 10 kDa subunit
Target Background
Enables RNA binding activity and splicing factor binding activity. Involved in mRNA splicing, via spliceosome. Located in nucleoplasm. Part of U12-type spliceosomal complex and U2-type precatalytic spliceosome.
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