Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against SFRP4 was raised in rabbit using the Recombinant Human Secreted frizzled-related protein 4 protein (293-346AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
The antibody against SFRP4 was raised in rabbit using the Recombinant Human Secreted frizzled-related protein 4 protein (293-346AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
$299.00
| Cat.No | ADC-13911A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SFRP4 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | FITC conjugated |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Secreted frizzled-related protein 4 protein (293-346AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6FHJ7 |
Uniprot Id
Q6FHJ7
Target Species
Human
Target Name
SFRP4
Target Full Name
Secreted frizzled-related protein 4
Target Function
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 plays a role in bone morphogenesis. May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling. Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake.
Target Involvement
Pyle disease (PYL)
Target Subcellular Location
Secreted. Note=Cytoplasmic in ovarian tumor cells.
Target Protein Families
Secreted frizzled-related protein (sFRP) family
Target Tissue Specificity
Expressed in mesenchymal cells. Highly expressed in the stroma of proliferative endometrium. Expressed in cardiomyocytes. Shows moderate to strong expression in ovarian tumors with expression increasing as the tumor stage increases. In ovarian tumors, exp
Target Synonyms
Frizzled protein; Frizzled protein human endometrium; FRP 4; FRP4; FrpHE; human endometrium; PYL; Secreted frizzled-related protein 4; sFRP-4; Sfrp4; SFRP4_HUMAN
Target Background
Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
