Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against SGCB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 94-318 of human SGCB (NP_000223.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SGCB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 94-318 of human SGCB (NP_000223.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-09398A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SGCB |
| Target Synonyms | A3b; SGC; LGMD2E; LGMDR4; SGCB | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, Rat heart, Mouse skeletal muscle, SKOV3 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 94-318 of human SGCB (NP_000223.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q16585 | Immunogen Sequence |
Uniprot Id
Q16585
Target Species
Human
Target Name
SGCB
Target Full Name
Beta-sarcoglycan
Target Function
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Target Involvement
Limb-girdle muscular dystrophy 2E (LGMD2E)
Target Subcellular Location
Cell membrane, sarcolemma; Single-pass type II membrane protein. Cytoplasm, cytoskeleton.
Target Protein Families
Sarcoglycan beta/delta/gamma/zeta family
Target Tissue Specificity
Highest expression in heart and skeletal muscle. Low expression in brain, kidney, placenta, pancreas and lung. High expression in fetal brain. Also found in fetal lung, kidney and liver.
Target Synonyms
43 kDa dystrophin associated glycoprotein; 43 kDa dystrophin-associated glycoprotein; 43DAG; A3b; Beta SG; Beta-sarcoglycan; Beta-SG; dystrophin-associated glycoprotein, 43-kD; LGMD2E; Limb girdle muscular dystrophy 2E (non linked families); Sarcoglycan beta; sarcoglycan, beta (43kDa dystrophin-associated glycoprotein); SGC; SGCB; SGCB_HUMAN
Target Background
This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
