Rabbit anti-Human SGCG Polyclonal Antibody

The antibody against SGCG was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 72-291 of human SGCG (NP_000222.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01621A

Number

Cat.No	ADA-01621A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	SGCG
Target Synonyms	A4; MAM; DMDA; SCG3; 35DAG; DAGA4; DMDA1; LGMD2C; LGMDR5; SCARMD2; gamma-SG; SGCG	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, MCF7	Application	ELISA, WB

Cat.No

ADA-01621A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

SGCG

Target Synonyms

A4; MAM; DMDA; SCG3; 35DAG; DAGA4; DMDA1; LGMD2C; LGMDR5; SCARMD2; gamma-SG; SGCG

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, MCF7

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 72-291 of human SGCG (NP_000222.1).	Target Species	Human
Uniprot ID	Q13326	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 72-291 of human SGCG (NP_000222.1).

Target Species

Human

Uniprot ID

Q13326

Immunogen Sequence

Background Information

Uniprot Id

Q13326
Target Species

Human
Target Name

SGCG
Target Full Name

Gamma-sarcoglycan
Target Function

Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Target Involvement

Limb-girdle muscular dystrophy 2C (LGMD2C)
Target Subcellular Location

Cell membrane, sarcolemma; Single-pass type II membrane protein. Cytoplasm, cytoskeleton.
Target Protein Families

Sarcoglycan beta/delta/gamma/zeta family
Target Tissue Specificity

Expressed in skeletal and heart muscle.
Target Synonyms

35 kDa dystrophin associated glycoprotein; 35 kDa dystrophin-associated glycoprotein; 35DAG; 35kD dystrophin associated glycoprotein; 35kDa dystrophin-associated glycoprotein; A4; DAGA4; DMDA; DMDA1; Gamma SG; Gamma-sarcoglycan; Gamma-SG; LGMD2C; MAM ; MGC130048; Sarcoglycan gamma; SCARMD2; SCG3; SGCG; SGCG_HUMAN; TYPE
Target Background

This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C).

Rabbit anti-Human SGCG Polyclonal Antibody

Specifications

Immunogen Information

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