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The antibody against SGCZ was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 83-312 of human SGCZ (NP_631906.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SGCZ was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 83-312 of human SGCZ (NP_631906.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-04717A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SGCZ |
| Target Synonyms | ZSG1; SGCZ | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, Rat heart | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 83-312 of human SGCZ (NP_631906.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q96LD1 | Immunogen Sequence |
Uniprot Id
Q96LD1
Target Species
Human
Target Name
SGCZ
Target Full Name
Zeta-sarcoglycan
Target Function
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. May play a role in the maintenance of striated muscle membrane stability.
Target Subcellular Location
Cell membrane, sarcolemma; Single-pass type II membrane protein. Cytoplasm, cytoskeleton.
Target Protein Families
Sarcoglycan beta/delta/gamma/zeta family
Target Synonyms
SGCZ; Zeta-sarcoglycan; Zeta-SG; ZSG1
Target Background
The zeta-sarcoglycan gene measures over 465 kb and localizes to 8p22. This protein is part of the sarcoglycan complex, a group of 6 proteins. The sarcoglycans are all N-glycosylated transmembrane proteins with a short intra-cellular domain, a single transmembrane region and a large extra-cellular domain containing a carboxyl-terminal cluster with several conserved cysteine residues. The sarcoglycan complex is part of the dystrophin-associated glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extra-cellular matrix.
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