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Rabbit anti-Human SGK2 Polyclonal Antibody

The antibody against SGK2 was raised in rabbit using the Human SGK2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-47201A

The antibody against SGK2 was raised in rabbit using the Human SGK2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$600.00

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Specifications


Cat.No ADC-47201A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSGK2
Target SynonymsSGK2 antibody; Serine/threonine-protein kinase Sgk2 antibody; EC 2.7.11.1 antibody; Serum/glucocorticoid-regulated kinase 2 antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium AzidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman SGK2Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9HBY8
Background Information
  • Uniprot Id

    Q9HBY8

  • Target Species

    Human

  • Target Name

    SGK2

  • Target Full Name

    Serine/threonine-protein kinase Sgk2

  • Target Function

    Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up-regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase.

  • Target Subcellular Location

    Cytoplasm. Nucleus.

  • Target Protein Families

    Protein kinase superfamily, AGC Ser/Thr protein kinase family

  • Target Tissue Specificity

    Highly expressed in liver, kidney and pancreas, and at lower levels in brain.

  • Target Synonyms

    SGK2; Serine/threonine-protein kinase Sgk2; EC 2.7.11.1; Serum/glucocorticoid-regulated kinase 2

  • Target Background

    This gene encodes a serine/threonine protein kinase. Although this gene product is similar to serum- and glucocorticoid-induced protein kinase (SGK), this gene is not induced by serum or glucocorticoids. This gene is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK. Alternative splicing results in multiple transcript variants.

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