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The antibody against SGSH was raised in rabbit using the Human SGSH as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against SGSH was raised in rabbit using the Human SGSH as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$600.00
| Cat.No | ADC-47199A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SGSH |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Human SGSH | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P51688 |
Uniprot Id
P51688
Target Species
Human
Target Name
SGSH
Target Full Name
N-sulphoglucosamine sulphohydrolase
Target Function
Catalyzes a step in lysosomal heparan sulfate degradation.
Target Involvement
Mucopolysaccharidosis 3A (MPS3A)
Target Subcellular Location
Lysosome.
Target Protein Families
Sulfatase family
Target Synonyms
Heparan sulfate sulfatase; Heparan sulphate sulphatase; HSS; MPS 3A; MPS3 A; MPS3A; Mucopolysaccharidosis type IIIA; N sulfoglucosamine sulfohydrolase (sulfamidase); N sulfoglucosamine sulfohydrolase; N-sulphoglucosamine sulphohydrolase; SFMD; SGSH; SPHM_HUMAN; Sulfoglucosamine sulfamidase; Sulphamidase; Sulphoglucosamine sulphamidase
Target Background
This gene encodes the enzyme sulfamidase; one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with the lysosomal storage disease mucopolysaccaridosis IIIA, also known as Sanfilippo syndrome A, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined.
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