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The antibody against SIGLEC11 was raised in rabbit using the Synthetic peptide of Human SIGLEC11 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against SIGLEC11 was raised in rabbit using the Synthetic peptide of Human SIGLEC11 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-25920A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SIGLEC11 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human SIGLEC11 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96RL6 |
Uniprot Id
Q96RL6
Target Species
Human
Target Name
SIGLEC11
Target Full Name
Sialic acid-binding Ig-like lectin 11
Target Function
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,8-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Protein Families
Immunoglobulin superfamily, SIGLEC (sialic acid binding Ig-like lectin) family
Target Tissue Specificity
Expressed by macrophages in various tissues including Kupffer cells. Also found in brain microglia.
Target Synonyms
sialic acid binding Ig like lectin 11; sialic acid binding lectin 11; Sialic acid-binding Ig-like lectin 11; Sialic acid-binding lectin 11; SIG11_HUMAN; Siglec 11; Siglec-11; SIGLEC11
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