Rabbit anti-Human SIK2 Polyclonal Antibody

The antibody against SIK2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 827-926 of human SIK2 (NP_056006.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-10923A

Number

Cat.No	ADA-10923A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	SIK2
Target Synonyms	QIK; SIK-2; SNF1LK2; LOH11CR1I; SIK2	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, A-549, HepG2, Jurkat, Mouse fat, Mouse testis, Rat testis, SW620, U-87MG	Application	ELISA, WB

Cat.No

ADA-10923A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

SIK2

Target Synonyms

QIK; SIK-2; SNF1LK2; LOH11CR1I; SIK2

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, A-549, HepG2, Jurkat, Mouse fat, Mouse testis, Rat testis, SW620, U-87MG

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 827-926 of human SIK2 (NP_056006.1).	Target Species	Human
Immunogen Sequence	PPPPPPRQPGAAPAPLQFSYQTCELPSAASPAPDYPTPCQYPVDGAQQSDLTGPDCPRSPGLQEAPSSYDPLALSELPGLFDCEMLDAVDPQHNGYVLVN	Uniprot ID	Q9H0K1

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 827-926 of human SIK2 (NP_056006.1).

Target Species

Human

Immunogen Sequence

PPPPPPRQPGAAPAPLQFSYQTCELPSAASPAPDYPTPCQYPVDGAQQSDLTGPDCPRSPGLQEAPSSYDPLALSELPGLFDCEMLDAVDPQHNGYVLVN

Uniprot ID

Q9H0K1

Background Information

Uniprot Id

Q9H0K1
Target Species

Human
Target Name

SIK2
Target Full Name

Serine/threonine-protein kinase SIK2
Target Function

Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.
Target Subcellular Location

Cytoplasm.
Target Protein Families

Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily
Target Synonyms

DKFZp434K1115; EC 2.7.11.1; KIAA0781; LOH11CR1I; QIK; Qin induced kinase; Qin-induced kinase; Salt inducible kinase 2; Salt inducible protein kinase 2; Salt inducible serine/threonine kinase 2; Salt-inducible protein kinase 2; Serine/threonine protein kinase SIK2; Serine/threonine protein kinase SNF1 like kinase 2; Serine/threonine-protein kinase SIK2; Serine/threonine-protein kinase SNF1-like kinase 2; SIK 2; SIK-2; SIK2; SIK2_HUMAN; SNF1 like kinase; SNF1 like kinase 2; SNF1LK2
Target Background

Enables ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Involved in intracellular signal transduction and protein autophosphorylation. Predicted to be located in nucleus. Predicted to be active in cytoplasm.

Rabbit anti-Human SIK2 Polyclonal Antibody

Specifications

Immunogen Information

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