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The antibody against SIRPB1 was raised in rabbit using the Recombinant Human Signal-regulatory protein beta-1 protein (30-371AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against SIRPB1 was raised in rabbit using the Recombinant Human Signal-regulatory protein beta-1 protein (30-371AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human thyroid tissue using SIRPB1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using SIRPB1 Antibody at dilution of 1:1002
Immunofluorescent analysis of Hela cells using SIRPB1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-15711A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SIRPB1 |
| Target Synonyms | SIRPB1 antibody; Signal-regulatory protein beta-1 antibody; SIRP-beta-1 antibody; CD172 antigen-like family member B antibody; CD antigen CD172b antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Signal-regulatory protein beta-1 protein (30-371AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O00241 |
Uniprot Id
O00241
Target Species
Human
Target Name
SIRPB1
Target Full Name
Signal-regulatory protein beta-1
Target Function
Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Tissue Specificity
Detected in monocytes and dendritic cells.
Target Research Area
Signal transduction
Target Synonyms
SIRPB1; Signal-regulatory protein beta-1; SIRP-beta-1; CD172 antigen-like family member B; CD antigen CD172b
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