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Rabbit anti-Human SLBP Polyclonal Antibody

The antibody against SLBP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 125-223 of human SLBP (NP_006518.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-07411A

The antibody against SLBP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 125-223 of human SLBP (NP_006518.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

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Specifications


Cat.No ADA-07411A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSLBP
Target SynonymsHBP; SLBPFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, Jurkat, Mouse testisApplicationELISA, WB, IHC-P

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 125-223 of human SLBP (NP_006518.1).Target SpeciesHuman
Immunogen SequencePADFETDESVLMRRQKQINYGKNTIAYDRYIKEVPRHLRQPGIHPKTPNKFKKYSRRSWDQQIKLWKVALHFWDPPAEEGCDLQEIHPVDLESAESSSEUniprot IDQ14493
Background Information
  • Uniprot Id

    Q14493

  • Target Species

    Human

  • Target Name

    SLBP

  • Target Full Name

    Histone RNA hairpin-binding protein

  • Target Function

    RNA-binding protein involved in the histone pre-mRNA processing. Binds the stem-loop structure of replication-dependent histone pre-mRNAs and contributes to efficient 3'-end processing by stabilizing the complex between histone pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP), via the histone downstream element (HDE). Plays an important role in targeting mature histone mRNA from the nucleus to the cytoplasm and to the translation machinery. Stabilizes mature histone mRNA and could be involved in cell-cycle regulation of histone gene expression. Involved in the mechanism by which growing oocytes accumulate histone proteins that support early embryogenesis. Binds to the 5' side of the stem-loop structure of histone pre-mRNAs

  • Target Subcellular Location

    Cytoplasm. Nucleus.

  • Target Protein Families

    SLBP family

  • Target Tissue Specificity

    Widely expressed.

  • Target Synonyms

    Hairpin binding protein histone; HBP; Histone binding protein; Histone RNA hairpin binding protein; Histone RNA hairpin-binding protein; Histone stem-loop-binding protein; SLBP; SLBP_HUMAN; Stem loop (histone) binding protein; Stem loop binding protein

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