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The antibody against SLC12A4 was raised in rabbit using the Recombinant Human Solute carrier family 12 member 4 protein (601-900AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against SLC12A4 was raised in rabbit using the Recombinant Human Solute carrier family 12 member 4 protein (601-900AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human adrenal gland tissue using SLC12A4 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue using SLC12A4 Antibody at dilution of 1:1002
| Cat.No | ADC-17712A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC12A4 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Solute carrier family 12 member 4 protein (601-900AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UP95 |
Uniprot Id
Q9UP95
Target Species
Human
Target Name
SLC12A4
Target Full Name
Solute carrier family 12 member 4
Target Function
Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl(-) exit in NaCl absorbing epithelia. Isoform 4 has no transport activity.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
SLC12A transporter family
Target Tissue Specificity
Ubiquitous. Levels are much higher in erythrocytes from patients with Hb SC and Hb SS compared to normal AA erythrocytes. This may contribute to red blood cell dehydration and to the manifestation of sickle cell disease by increasing the intracellular con
Target Synonyms
Electroneutral potassium chloride cotransporter 1; Electroneutral potassium-chloride cotransporter 1; Erythroid K Cl cotransporter 1; Erythroid K-Cl cotransporter 1; FLJ40489; hKCC 1; hKCC1; KCC 1; KCC1; Potassium transport protein; Potassium/chloride cotransporter 1; S12A4_HUMAN; Slc12a4; Solute carrier family 12 (potassium/chloride transporters) member 4; Solute carrier family 12 member 4
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