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The antibody against SLC14A1 was raised in rabbit using the Recombinant Human Urea transporter 1 protein (1-51AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against SLC14A1 was raised in rabbit using the Recombinant Human Urea transporter 1 protein (1-51AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-06656A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC14A1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Urea transporter 1 protein (1-51AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q13336 |
Uniprot Id
Q13336
Target Species
Human
Target Name
SLC14A1
Target Full Name
Urea transporter 1
Target Function
Urea channel that facilitates transmembrane urea transport down a concentration gradient. A constriction of the transmembrane channel functions as selectivity filter through which urea is expected to pass in dehydrated form. The rate of urea conduction is increased by hypotonic stress. Plays an important role in the kidney medulla collecting ducts, where it allows rapid equilibration between the lumen of the collecting ducts and the interstitium, and thereby prevents water loss driven by the high concentration of urea in the urine. Facilitates urea transport across erythrocyte membranes. May also play a role in transmembrane water transport, possibly by indirect means.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.
Target Protein Families
Urea transporter family
Target Tissue Specificity
Detected in erythrocytes (at protein level). Erythrocytes.
Target Synonyms
blood group Kidd urea transporter; erythrocyte; HsT1341; HUT11; JK; Kidd; kidd (JK) blood group urea transporter B1; RACH1; Slc14a1; solute carrier family 14 (urea transporter) member 1 (Kidd blood group); Solute carrier family 14 member 1; Urea transporter 1; Urea transporter; urea transporter B1; Urea transporter erythrocyte; urea transporter JK glycoprotein; UT B1; UT1; UT1_HUMAN; UTE
Target Background
The protein encoded by this gene is a membrane transporter that mediates urea transport in erythrocytes. This gene forms the basis for the Kidd blood group system.
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