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Rabbit anti-Human SLC14A1 Polyclonal Antibody

The antibody against SLC14A1 was raised in rabbit using the Recombinant Human Urea transporter 1 protein (1-51AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.

ADC-06656A

The antibody against SLC14A1 was raised in rabbit using the Recombinant Human Urea transporter 1 protein (1-51AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.

$299.00

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Specifications


Cat.No ADC-06656A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSLC14A1
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Urea transporter 1 protein (1-51AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ13336
Background Information
  • Uniprot Id

    Q13336

  • Target Species

    Human

  • Target Name

    SLC14A1

  • Target Full Name

    Urea transporter 1

  • Target Function

    Urea channel that facilitates transmembrane urea transport down a concentration gradient. A constriction of the transmembrane channel functions as selectivity filter through which urea is expected to pass in dehydrated form. The rate of urea conduction is increased by hypotonic stress. Plays an important role in the kidney medulla collecting ducts, where it allows rapid equilibration between the lumen of the collecting ducts and the interstitium, and thereby prevents water loss driven by the high concentration of urea in the urine. Facilitates urea transport across erythrocyte membranes. May also play a role in transmembrane water transport, possibly by indirect means.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    Urea transporter family

  • Target Tissue Specificity

    Detected in erythrocytes (at protein level). Erythrocytes.

  • Target Synonyms

    blood group Kidd urea transporter; erythrocyte; HsT1341; HUT11; JK; Kidd; kidd (JK) blood group urea transporter B1; RACH1; Slc14a1; solute carrier family 14 (urea transporter) member 1 (Kidd blood group); Solute carrier family 14 member 1; Urea transporter 1; Urea transporter; urea transporter B1; Urea transporter erythrocyte; urea transporter JK glycoprotein; UT B1; UT1; UT1_HUMAN; UTE

  • Target Background

    The protein encoded by this gene is a membrane transporter that mediates urea transport in erythrocytes. This gene forms the basis for the Kidd blood group system.

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