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Rabbit anti-Human SLC22A9 Polyclonal Antibody

The antibody against SLC22A9 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 40-145 of human SLC22A9 (NP_543142.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01518A

The antibody against SLC22A9 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 40-145 of human SLC22A9 (NP_543142.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-01518A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSLC22A9
Target SynonymsOAT4; OAT7; ust3; HOAT4; UST3H; SLC22A9FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, Mouse kidney, HepG2, Mouse liver, U-87MGApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 40-145 of human SLC22A9 (NP_543142.2).Target SpeciesHuman
Immunogen SequenceFTAFIPGHRCWVHILDNDTVSDNDTGALSQDALLRISIPLDSNMRPEKCRRFVHPQWQLLHLNGTFPNTSDADMEPCVDGWVYDRISFSSTIVTEWDLVCDSQSLTUniprot IDQ8IVM8
Background Information
  • Uniprot Id

    Q8IVM8

  • Target Species

    Human

  • Target Name

    SLC22A9

  • Target Full Name

    Organic anion transporter 7

  • Target Function

    Sodium-independent organic anion transporter which exhibits high specificity for sulfated conjugates of xenobiotics and steroid hormones. It is also specifically activated by 3 to 5 carbons-containing short-chain fatty acids/SCFAs, including propionate, butyrate and valerate. May operate the exchange of sulfated organic components against short-chain fatty acids/SCFAs at the sinusoidal membrane of hepatocytes.

  • Target Subcellular Location

    Basolateral cell membrane; Multi-pass membrane protein. Note=Enriched at the sinusoidal part of the plasma membrane.

  • Target Protein Families

    Major facilitator (TC 2.A.1) superfamily, Organic cation transporter (TC 2.A.1.19) family

  • Target Tissue Specificity

    Specifically expressed in liver by hepatocytes (at protein level).

  • Target Synonyms

    SLC22A9; hOAT4; OAT7; UST3; Solute carrier family 22 member 9; Organic anion transporter 7

  • Target Background

    Enables anion:anion antiporter activity; short-chain fatty acid transmembrane transporter activity; and sodium-independent organic anion transmembrane transporter activity. Involved in hormone transport; short-chain fatty acid import; and sodium-independent organic anion transport. Located in basolateral plasma membrane.

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