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The antibody against SLC23A1 was raised in rabbit using the Recombinant Human Solute carrier family 23 member 1 protein (173-259AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against SLC23A1 was raised in rabbit using the Recombinant Human Solute carrier family 23 member 1 protein (173-259AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry of paraffin-embedded human small intestine tissue using SLC23A1 Antibody at dilution of 1:1002
| Cat.No | ADC-22441A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC23A1 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Solute carrier family 23 member 1 protein (173-259AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UHI7 |
Uniprot Id
Q9UHI7
Target Species
Human
Target Name
SLC23A1
Target Full Name
Solute carrier family 23 member 1
Target Function
Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
Xanthine/uracil permease family, Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily
Target Tissue Specificity
Highly expressed in adult small intestine, kidney, thymus, ovary, colon, prostate and liver, and in fetal kidney, liver and thymus.
Target Synonyms
hSVCT1; Na(+)/L-ascorbic acid transporter 1; S23A1_HUMAN; Slc23a1; Sodium-dependent vitamin C transporter 1; solute carrier family 23 (nucleobase transporters); member 1; Solute carrier family 23 member 1; SVCT1; Yolk sac permease-like molecule 3; YSPL3
Target Background
The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two transporters. The encoded protein is active in bulk vitamin C transport involving epithelial surfaces. Previously, this gene had an official symbol of SLC23A2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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