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Rabbit anti-Human SLC25A21 Polyclonal Antibody

The antibody against SLC25A21 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 148-247 of human SLC25A21(NP_085134.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-08152A

The antibody against SLC25A21 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 148-247 of human SLC25A21(NP_085134.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

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Specifications


Cat.No ADA-08152A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSLC25A21
Target SynonymsODC; ODC1; MTDPS18; SLC25A21FormLiquid
Species ReactivityHuman, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.05% proclin300, pH7.3.Purification MethodAffinity purification
Positive SamplesK-562ApplicationELISA, WB, IHC-P

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 148-247 of human SLC25A21(NP_085134.1).Target SpeciesHuman
Immunogen SequencePSTVGYARQIIKKEGWGLQGLNKGLTATLGRHGVFNMVYFGFYYNVKNMIPVNKDPILEFWRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYUniprot IDQ9BQT8
Background Information
  • Uniprot Id

    Q9BQT8

  • Target Species

    Human

  • Target Name

    SLC25A21

  • Target Full Name

    Mitochondrial 2-oxodicarboxylate carrier

  • Target Function

    Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2-oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate.

  • Target Subcellular Location

    Mitochondrion inner membrane; Multi-pass membrane protein.

  • Target Protein Families

    Mitochondrial carrier (TC 2.A.29) family

  • Target Tissue Specificity

    Expressed in placenta, gall bladder and colon.

  • Target Synonyms

    SLC25A21; ODC; Mitochondrial 2-oxodicarboxylate carrier; Solute carrier family 25 member 21

  • Target Background

    SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.

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