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The antibody against SLC26A8 was raised in rabbit using the Recombinant Human Testis anion transporter 1 protein (414-595AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against SLC26A8 was raised in rabbit using the Recombinant Human Testis anion transporter 1 protein (414-595AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human testis tissue using SLC26A8 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human pancreatic cancer using SLC26A8 Antibody at dilution of 1:1002
Immunofluorescent analysis of HepG2 cells using SLC26A8 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-18591A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC26A8 |
| Target Synonyms | SLC26A8 antibody; TAT1 antibody; Testis anion transporter 1 antibody; Anion exchange transporter antibody; Solute carrier family 26 member 8 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Testis anion transporter 1 protein (414-595AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96RN1 |
Uniprot Id
Q96RN1
Target Species
Human
Target Name
SLC26A8
Target Full Name
Testis anion transporter 1
Target Function
Acts as a DIDS-sensitive anion exchanger mediating chloride, sulfate and oxalate transport. May fulfill critical anion exchange functions in male germ line during meiosis and hence may play a role in spermatogenesis. May be involved in a new regulatory pathway linking sulfate transport to RhoGTPase signaling in male germ cells. A critical component of the sperm annulus that is essential for correct sperm tail differentiation and motility and hence male fertility. May form a molecular complex involved in the regulation of chloride and bicarbonate ions fluxes during sperm capacitation.
Target Involvement
Spermatogenic failure 3 (SPGF3)
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
SLC26A/SulP transporter (TC 2.A.53) family
Target Tissue Specificity
Expression observed exclusively in testis, restricted to the meiotic phase of the germ cell. Abundant expression located in the seminiferous tubules, concentrated on the luminal side of the tubuli harboring the spermatocytes and spermatids. Expressed in s
Target Synonyms
SLC26A8; TAT1; Testis anion transporter 1; Anion exchange transporter; Solute carrier family 26 member 8
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