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The antibody against SLC35D2 was raised in rabbit using the Recombinant Human UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter protein (75-146AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against SLC35D2 was raised in rabbit using the Recombinant Human UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter protein (75-146AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human ovarian cancer using SLC35D2 Antibody at dilution of 1:100
| Cat.No | ADC-19533A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC35D2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter protein (75-146AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q76EJ3 |
Uniprot Id
Q76EJ3
Target Species
Human
Target Name
SLC35D2
Target Full Name
Nucleotide sugar transporter SLC35D2
Target Function
Antiporter transporting nucleotide sugars such as UDP-N-acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP-mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling.
Target Subcellular Location
Golgi apparatus membrane; Multi-pass membrane protein.
Target Protein Families
TPT transporter family, SLC35D subfamily
Target Tissue Specificity
Highly expressed in heart, kidney, small intestine, placenta, lung and peripheral blood leukocyte. Weakly expressed in skeletal muscle and spleen. Not expressed in brain, colon and thymus.
Target Synonyms
Fringe connection; HFRC 1; Hfrc; HFRC1; Homolog of Fringe connection protein 1; MGC117215; MGC142139; Nucleotide sugar transporter UGTrel8; S35D2_HUMAN; SLC35D2; Solute carrier family 35 member D2; SQV 7L; SQV7-like protein; SQV7L; UDP N acetylglucosamine transporter; UDP-galactose transporter-related protein 8; UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter; UGTrel 8; UGTrel8
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