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The antibody against SLC52A3 was raised in rabbit using the Recombinant Human Solute carrier family 52, riboflavin transporter, member 3 protein (159-220AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against SLC52A3 was raised in rabbit using the Recombinant Human Solute carrier family 52, riboflavin transporter, member 3 protein (159-220AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry of paraffin-embedded human testis tissue using SLC52A3 Antibody at dilution of 1:1002
| Cat.No | ADC-14179A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC52A3 |
| Target Synonyms | member 3 antibody, member 3 antibody; S52A3_HUMAN antibody; Slc52a3 antibody; solute carrier family 52 (riboflavin transporter), member 3 antibody; Solute carrier family 52 antibody; solute carrier family 52, riboflavin transporter | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Solute carrier family 52, riboflavin transporter, member 3 protein (159-220AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NQ40 |
Uniprot Id
Q9NQ40
Target Species
Human
Target Name
SLC52A3
Target Full Name
Solute carrier family 52, riboflavin transporter, member 3
Target Function
Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism. Humans are unable to synthesize vitamin B2/riboflavin and must obtain it via intestinal absorption.
Target Involvement
Brown-Vialetto-Van Laere syndrome 1 (BVVLS1); Fazio-Londe disease (FALOND)
Target Subcellular Location
Apical cell membrane; Multi-pass membrane protein. Cell membrane.; [Isoform 1]: Cell membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein. Cytoplasm.; [Isoform 2]: Cytoplasm.
Target Protein Families
Riboflavin transporter family
Target Tissue Specificity
Predominantly expressed in testis. Highly expressed in small intestine and prostate.
Target Synonyms
bA371L19.1; BVVLS; BVVLS1; C20orf54; C20orf54provided by HGNC; Chromosome 20 open reading frame 54; hRFT2; member 3; MGC10698; RFT2; RFVT3; Riboflavin transporter 2; riboflavin transporter; riboflavin transporter, member 3; S52A3_HUMAN; Slc52a3; solute carrier family 52 (riboflavin transporter), member 3; Solute carrier family 52; solute carrier family 52, riboflavin transporter, member 3
Target Background
This gene encodes a riboflavin transporter protein that is strongly expressed in the intestine and likely plays a role in intestinal absorption of riboflavin. The protein is predicted to have eleven transmembrane domains and a cell surface localization signal in the C-terminus. Mutations at this locus have been associated with Brown-Vialetto-Van Laere syndrome and Fazio-Londe disease.
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