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The antibody against SLC6A11 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-60 of human SLC6A11 (NP_055044.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SLC6A11 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-60 of human SLC6A11 (NP_055044.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-02026A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC6A11 |
| Target Synonyms | GAT3; GAT4; GAT-3; SLC6A11 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-60 of human SLC6A11 (NP_055044.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MTAEKALPLGNGKAAEEARESEAPGGGCSSGGAAPARHPRVKRDKAVHERGHWNNKVEFV | Uniprot ID | P48066 |
Uniprot Id
P48066
Target Species
Human
Target Name
SLC6A11
Target Full Name
Sodium- and chloride-dependent GABA transporter 3
Target Function
Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A11 subfamily
Target Tissue Specificity
Widespread distribution in the brain.
Target Synonyms
GABT3; GAT-3; GAT3; S6A11_HUMAN; Slc6a11; Sodium- and chloride-dependent GABA transporter 3; Solute carrier family 6 member 11
Target Background
The protein encoded by this gene is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which ends the GABA neurotransmission. Defects in this gene may result in epilepsy, behavioral problems, or intellectual problems. Two transcript variants encoding different isoforms have been found for this gene.
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