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The antibody against SLC6A15 was raised in rabbit using the Recombinant Human Sodium-dependent neutral amino acid transporter B(0)AT2 protein (357-452AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against SLC6A15 was raised in rabbit using the Recombinant Human Sodium-dependent neutral amino acid transporter B(0)AT2 protein (357-452AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human bladder cancer using SLC6A15 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human prostate cancer using SLC6A15 Antibody at dilution of 1:1002
Immunofluorescent analysis of HepG2 cells using SLC6A15 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-18155A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC6A15 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Sodium-dependent neutral amino acid transporter B(0)AT2 protein (357-452AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H2J7 |
Uniprot Id
Q9H2J7
Target Species
Human
Target Name
SLC6A15
Target Full Name
Sodium-dependent neutral amino acid transporter B(0)AT2
Target Function
Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A15 subfamily
Target Tissue Specificity
Almost exclusively expressed in the brain.
Target Synonyms
hv7 3; MGC87066; NTT73; Orphan sodium and chloride dependent neurotransmitter transporter NTT73; Orphan transporter v7 3; S6A15_HUMAN; SBAT1; SLC6A15; sodium- and chloride-dependent neurotransmitter transporter NTT73; Sodium-coupled branched-chain amino-acid transporter 1; Sodium-dependent neutral amino acid transporter B(0)AT2; Solute carrier family 6 (neutral amino acid transporter) member 15; Solute carrier family 6 member 15; Transporter v7-3; V7 3
Target Background
This gene encodes a member of the solute carrier family 6 protein family which transports neutral amino acids. The encoded protein is thought to play a role in neuronal amino acid transport (PMID: 16185194) and may be associated with major depression (PMID: 21521612). Multiple transcript variants encoding different isoforms have been found for this gene.
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