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The antibody against SLC6A19 was raised in rabbit using the Recombinant Human Sodium-dependent neutral amino acid transporter B(0)AT1 protein (326-413AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against SLC6A19 was raised in rabbit using the Recombinant Human Sodium-dependent neutral amino acid transporter B(0)AT1 protein (326-413AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-04048A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC6A19 |
| Target Synonyms | SLC6A19 antibody; B0AT1 antibody; Sodium-dependent neutral amino acid transporter B(0)AT1 antibody; Solute carrier family 6 member 19 antibody; System B(0) neutral amino acid transporter AT1 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Sodium-dependent neutral amino acid transporter B(0)AT1 protein (326-413AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q695T7 |
Uniprot Id
Q695T7
Target Species
Human
Target Name
SLC6A19
Target Full Name
Sodium-dependent neutral amino acid transporter B(0)AT1
Target Function
Transporter that mediates resorption of neutral amino acids across the apical membrane of renal and intestinal epithelial cells. This uptake is sodium-dependent and chloride-independent. Requires CLTRN in kidney or ACE2 in intestine for cell surface expression and amino acid transporter activity.
Target Involvement
Hartnup disorder (HND); Hyperglycinuria (HG); Iminoglycinuria (IG)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein.
Target Protein Families
Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A19 subfamily
Target Tissue Specificity
Robust expression in kidney and small intestine, with minimal expression in pancreas. Also expressed in stomach, liver, duodenum, ileocecum, colon and prostate. Not detected in testis, whole brain, cerebellum, fetal liver, spleen, skeletal muscle, uterus,
Target Synonyms
SLC6A19; B0AT1; Sodium-dependent neutral amino acid transporter B(0)AT1; Solute carrier family 6 member 19; System B(0) neutral amino acid transporter AT1
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