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The antibody against SLC6A8 was raised in rabbit using the Synthetic peptide of Human SLC6A8 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against SLC6A8 was raised in rabbit using the Synthetic peptide of Human SLC6A8 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-25859A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC6A8 |
| Target Synonyms | creatine), member 8. antibody; Solute carrier family 6 member 8 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human SLC6A8 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P48029 |
Uniprot Id
P48029
Target Species
Human
Target Name
SLC6A8
Target Full Name
Sodium- and chloride-dependent creatine transporter 1
Target Function
Required for the uptake of creatine in muscles and brain.
Target Involvement
Cerebral creatine deficiency syndrome 1 (CCDS1)
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A8 subfamily
Target Tissue Specificity
Predominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testis and prostate.
Target Synonyms
SLC6A 8; SLC6A8; Creatine transporter 1; Creatine transporter SLC6A8; CRT; CRTR; CT 1; CT1; MGC87396; SC6A8_HUMAN; Slc6a8; Sodium and chloride-dependent creatine transporter 1; Sodium- and chloride-dependent creatine transporter 1; Solute carrier family 6 (neurotransmitter transporter, creatine), member 8.; Solute carrier family 6 member 8
Target Background
The protein encoded by this gene is a plasma membrane protein whose function is to transport creatine into and out of cells. Defects in this gene can result in X-linked creatine deficiency syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.
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