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Rabbit anti-Human SLC6A9 Polyclonal Antibody

The antibody against SLC6A9 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human SLC6A9 (NP_964012.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-11345A

The antibody against SLC6A9 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human SLC6A9 (NP_964012.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-11345A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSLC6A9
Target SynonymsGLYT1; GCENSG; SLC6A9FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.05% proclin300, pH7.3.Purification MethodAffinity purification
Positive SamplesC6, K-562, MCF7, Mouse liverApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human SLC6A9 (NP_964012.2).Target SpeciesHuman
Immunogen SequenceMSGGDTRAAIARPRMAAAHGPVAPSSPEQVTLLPVQRSFFLPPFSGATPSTSLAESVLKVWHGAYNSGLLPQLMAQHSLAMAQNGAVPSEATKRDQNLKRGNWGNQIEFVUniprot IDP48067
Background Information
  • Uniprot Id

    P48067

  • Target Species

    Human

  • Target Name

    SLC6A9

  • Target Full Name

    Sodium- and chloride-dependent glycine transporter 1

  • Target Function

    Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May play a role in regulation of glycine levels in NMDA receptor-mediated neurotransmission.

  • Target Involvement

    Glycine encephalopathy with normal serum glycine (GCENSG)

  • Target Subcellular Location

    Membrane; Multi-pass membrane protein.

  • Target Protein Families

    Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A9 subfamily

  • Target Tissue Specificity

    Isoform GlyT-1A and isoform GlyT-1B can be found in brain, kidney, pancreas, lung, placenta and liver but isoform GlyT-1C is only found in brain.

  • Target Synonyms

    glycine transporter 1; Glyt 1; GlyT-1; GlyT1; SC6A9_HUMAN; SLC6A9; Sodium and chloride dependent glycine transporter 1; Sodium- and chloride-dependent glycine transporter 1; Solute carrier family 6 member 9

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