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Rabbit anti-Human SLC9A8 Polyclonal Antibody

The antibody against SLC9A8 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 472-581 of human SLC9A8 (NP_056081.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03267A

The antibody against SLC9A8 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 472-581 of human SLC9A8 (NP_056081.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-03267A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSLC9A8
Target SynonymsNHE8; NHE-8; SLC9A8FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive Samples293TApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 472-581 of human SLC9A8 (NP_056081.1).Target SpeciesHuman
Immunogen SequenceRLMDIEDAKAHRRNKKDVNLSKTEKMGNTVESEHLSELTEEEYEAHYIRRQDLKGFVWLDAKYLNPFFTRRLTQEDLHHGRIQMKTLTNKWYEEVRQGPSGSEDDEQELLUniprot IDQ9Y2E8
Background Information
  • Uniprot Id

    Q9Y2E8

  • Target Species

    Human

  • Target Name

    SLC9A8

  • Target Full Name

    Sodium/hydrogen exchanger 8

  • Target Function

    Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.

  • Target Subcellular Location

    Golgi apparatus membrane; Multi-pass membrane protein.

  • Target Protein Families

    Monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family

  • Target Tissue Specificity

    Ubiquitous. Strongly expressed in skeletal muscle and kidney.

  • Target Synonyms

    NHE8; NHE-8; SLC9A8

  • Target Background

    Sodium-hydrogen exchangers (NHEs), such as SLC9A8, are integral transmembrane proteins that exchange extracellular Na+ for intracellular H+. NHEs have multiple functions, including intracellular pH homeostasis, cell volume regulation, and electroneutral NaCl absorption in epithelia (Xu et al., 2008 [PubMed 18209477]).

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