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Rabbit anti-Human SLCO1A2 Polyclonal Antibody

The antibody against SLCO1A2 was raised in rabbit using the Recombinant Human Solute carrier organic anion transporter family member 1A2 protein (406-513AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.

ADC-05037A

The antibody against SLCO1A2 was raised in rabbit using the Recombinant Human Solute carrier organic anion transporter family member 1A2 protein (406-513AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.

$299.00

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Specifications


Cat.No ADC-05037A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSLCO1A2
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IFStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Solute carrier organic anion transporter family member 1A2 protein (406-513AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP46721
Background Information
  • Uniprot Id

    P46721

  • Target Species

    Human

  • Target Name

    SLCO1A2

  • Target Full Name

    Solute carrier organic anion transporter family member 1A2

  • Target Function

    Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids. Selectively inhibited by the grapefruit juice component naringin.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    Organo anion transporter (TC 2.A.60) family

  • Target Synonyms

    OATP; OATP-1; OATP-A; OATP1A2; Organic anion-transporting polypeptide 1; SLC21A3; SLCO1A2; SO1A2_HUMAN; Sodium-independent organic anion transporter; Solute carrier family 21 member 3; Solute carrier organic anion transporter family member 1A2

  • Target Background

    This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternative splicing of this gene results in multiple transcript variants.

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