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The antibody against SLCO1B3 was raised in rabbit using the Recombinant Human Solute carrier organic anion transporter family member 1B3 protein (648-695AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against SLCO1B3 was raised in rabbit using the Recombinant Human Solute carrier organic anion transporter family member 1B3 protein (648-695AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human liver tissue using SLCO1B3 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human liver cancer using SLCO1B3 Antibody at dilution of 1:1002
Immunofluorescent analysis of HepG2 cells using SLCO1B3 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-13679A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLCO1B3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Solute carrier organic anion transporter family member 1B3 protein (648-695AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NPD5 |
Uniprot Id
Q9NPD5
Target Species
Human
Target Name
SLCO1B3
Target Full Name
Solute carrier organic anion transporter family member 1B3
Target Function
Mediates the Na(+)-independent uptake of organic anions such as 17-beta-glucuronosyl estradiol, taurocholate, triiodothyronine (T3), leukotriene C4, dehydroepiandrosterone sulfate (DHEAS), methotrexate and sulfobromophthalein (BSP). Involved in the clearance of bile acids and organic anions from the liver.
Target Involvement
Hyperbilirubinemia, Rotor type (HBLRR)
Target Subcellular Location
Basolateral cell membrane; Multi-pass membrane protein.
Target Protein Families
Organo anion transporter (TC 2.A.60) family
Target Tissue Specificity
Highly expressed in liver, in particular at the basolateral membrane of hepatocytes near the central vein. Not detected in other tissues. Highly expressed in some cancer cell lines derived from colon, pancreas, liver and gall bladder.
Target Synonyms
HBLRR; Liver-specific organic anion transporter 2; LST-2; LST-3TM13; LST3; OATP-8; OATP1B3; Organic anion transporter 8; Organic anion-transporting polypeptide 8; SLC21A8; SLCO1B3; SO1B3_HUMAN; Solute carrier family 21 member 8; Solute carrier organic anion transporter family member 1B3
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