Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against SLIT1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1315-1534 of human SLIT1 (NP_003052.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SLIT1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1315-1534 of human SLIT1 (NP_003052.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-00288A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLIT1 |
| Target Synonyms | MEGF4; SLIL1; SLIT3; SLIT-1; SLIT1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1315-1534 of human SLIT1 (NP_003052.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O75093 | Immunogen Sequence |
Uniprot Id
O75093
Target Species
Human
Target Name
SLIT1
Target Full Name
Slit homolog 1 protein
Target Function
Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.
Target Subcellular Location
Secreted.
Target Tissue Specificity
Predominantly expressed in adult forebrain. Expressed in fetal brain, lung and kidney.
Target Synonyms
KIAA0813; MEGF 4; MEGF4; MGC164811; Multiple EGF-like domains protein 4; Multiple epidermal growth factor like domains 4; Multiple epidermal growth factor-like domains protein 4; OTTHUMP00000059392; SLIL 1; SLIL1; Slit 1; SLIT 3; Slit homolog 1; Slit homolog 1 protein; Slit-1; Slit1; SLIT1_HUMAN; SLIT3
Target Background
Enables Roundabout binding activity. Involved in axon extension involved in axon guidance; motor neuron axon guidance; and negative chemotaxis. Predicted to be located in extracellular region. Predicted to be active in extracellular space.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
