Rabbit anti-Human SMC1B Polyclonal Antibody

The antibody against SMC1B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1012-1161 of human SMC1B (NP_001278430.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03326A

Number

Cat.No	ADA-03326A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	SMC1B
Target Synonyms	SMC1L2; SMC1BETA; SMC1B	Form	Liquid
Species Reactivity	Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Rat testis	Application	ELISA, WB

Cat.No

ADA-03326A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

SMC1B

Target Synonyms

SMC1L2; SMC1BETA; SMC1B

Form

Liquid

Species Reactivity

Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Rat testis

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1012-1161 of human SMC1B (NP_001278430.1).	Target Species	Human
Immunogen Sequence	ILLKTAAPNLRALENLKTVRDKFQESTDAFEASRKEARLCRQEFEQVKKRRYDLFTQCFEHVSISIDQIYKKLCRNNSAQVSSYIKEQTQDQFQMIVISLKEEFYSRADALIGIYPEYDDCMFSRVLTLDLSQYPDTEGQESSKRHGESR	Uniprot ID	Q8NDV3

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1012-1161 of human SMC1B (NP_001278430.1).

Target Species

Human

Immunogen Sequence

ILLKTAAPNLRALENLKTVRDKFQESTDAFEASRKEARLCRQEFEQVKKRRYDLFTQCFEHVSISIDQIYKKLCRNNSAQVSSYIKEQTQDQFQMIVISLKEEFYSRADALIGIYPEYDDCMFSRVLTLDLSQYPDTEGQESSKRHGESR

Uniprot ID

Q8NDV3

Background Information

Uniprot Id

Q8NDV3
Target Species

Human
Target Name

SMC1B
Target Full Name

Structural maintenance of chromosomes protein 1B
Target Function

Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.
Target Subcellular Location

Nucleus. Chromosome. Chromosome, centromere.
Target Protein Families

SMC family, SMC1 subfamily
Target Synonyms

bK268H5; SMC protein 1B; SMC-1-beta; SMC-1B; SMC1 beta; SMC1B; SMC1B_HUMAN; SMC1beta; SMC1beta protein; Smc1l2; Structural maintenance of chromosomes 1-like 2; Structural maintenance of chromosomes 1B; Structural maintenance of chromosomes protein 1B
Target Background

SMC1L2 belongs to a family of proteins required for chromatid cohesion and DNA recombination during meiosis and mitosis (3:Revenkova et al., 2001 [PubMed 11564881]).

Rabbit anti-Human SMC1B Polyclonal Antibody

Specifications

Immunogen Information

Inquire Rabbit anti-Human SMC1B Polyclonal Antibody Now

Related Products