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The antibody against SMG8 was raised in rabbit using the Synthetic peptide of Human SMG8 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against SMG8 was raised in rabbit using the Synthetic peptide of Human SMG8 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-27734A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SMG8 |
| Target Synonyms | SMG8 antibody; ABC2 antibody; C17orf71 antibody; Protein SMG8 antibody; Amplified in breast cancer gene 2 protein antibody; Protein smg-8 homolog antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human SMG8 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8ND04 |
Uniprot Id
Q8ND04
Target Species
Human
Target Name
SMG8
Target Full Name
Nonsense-mediated mRNA decay factor SMG8
Target Function
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity.
Target Protein Families
SMG8 family
Target Synonyms
SMG8; ABC2; C17orf71; Protein SMG8; Amplified in breast cancer gene 2 protein; Protein smg-8 homolog
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