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The antibody against SMNDC1 was raised in rabbit using the Recombinant Human Survival of motor neuron-related-splicing factor 30 protein (1-238AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IP.
The antibody against SMNDC1 was raised in rabbit using the Recombinant Human Survival of motor neuron-related-splicing factor 30 protein (1-238AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IP.
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Immunohistochemistry of paraffin-embedded human heart tissue using SMNDC1 Antibody at dilution of 1:100
| Cat.No | ADC-21399A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SMNDC1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, IP | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Survival of motor neuron-related-splicing factor 30 protein (1-238AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O75940 |
Uniprot Id
O75940
Target Species
Human
Target Name
SMNDC1
Target Full Name
Survival of motor neuron-related-splicing factor 30
Target Function
Involved in spliceosome assembly.
Target Subcellular Location
Nucleus speckle. Nucleus, Cajal body.
Target Protein Families
SMN family
Target Tissue Specificity
Detected at intermediate levels in skeletal muscle, and at low levels in heart and pancreas.
Target Synonyms
30 kDa splicing factor SMNrp; MGC106917; MGC112663; SMN related protein; SMN-related protein; smndc1; SMNR; SPF30; SPF30_HUMAN; Splicing factor 30, survival of motor neuron-related; Survival motor neuron domain containing 1; Survival motor neuron domain containing protein 1; Survival motor neuron domain-containing protein 1; Survival of motor neuron related splicing factor 30; Survival of motor neuron-related-splicing factor 30
Target Background
This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene.
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