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Rabbit anti-Human SMPDL3A Polyclonal Antibody

The antibody against SMPDL3A was raised in rabbit using the Recombinant Human Acid sphingomyelinase-like phosphodiesterase 3a protein (51-350AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

ADC-23497A

The antibody against SMPDL3A was raised in rabbit using the Recombinant Human Acid sphingomyelinase-like phosphodiesterase 3a protein (51-350AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-23497A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSMPDL3A
Target SynonymsSMPDL3A antibody; ASML3AAcid sphingomyelinase-like phosphodiesterase 3a antibody; ASM-like phosphodiesterase 3a antibody; EC 3.1.4.- antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Acid sphingomyelinase-like phosphodiesterase 3a protein (51-350AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ92484
Background Information
  • Uniprot Id

    Q92484

  • Target Species

    Human

  • Target Name

    SMPDL3A

  • Target Full Name

    Cyclic GMP-AMP phosphodiesterase SMPDL3A

  • Target Function

    Has in vitro nucleotide phosphodiesterase activity with nucleoside triphosphates, such as ATP. Has in vitro activity with p-nitrophenyl-TMP. Has lower activity with nucleoside diphosphates, and no activity with nucleoside monophosphates. Has in vitro activity with CDP-choline, giving rise to CMP and phosphocholine. Has in vitro activity with CDP-ethanolamine. Does not have sphingomyelin phosphodiesterase activity.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Acid sphingomyelinase family

  • Target Tissue Specificity

    Detected in blood serum. Detected in macrophages (at protein level).

  • Target Synonyms

    SMPDL3A; ASML3AAcid sphingomyelinase-like phosphodiesterase 3a; ASM-like phosphodiesterase 3a; EC 3.1.4.-

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