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The antibody against SMYD1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human SMYD1 (NP_938015.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SMYD1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human SMYD1 (NP_938015.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-02579A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SMYD1 |
| Target Synonyms | BOP; KMT3D; ZMYND18; ZMYND22; SMYD1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat heart, HepG2, MCF7, Mouse skeletal muscle, Raji, Rat skeletal muscle | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human SMYD1 (NP_938015.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q8NB12 | Immunogen Sequence |
Uniprot Id
Q8NB12
Target Species
Human
Target Name
SMYD1
Target Full Name
Histone-lysine N-methyltransferase SMYD1
Target Function
Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
Class V-like SAM-binding methyltransferase superfamily
Target Tissue Specificity
Expression seems mostly restricted to heart and skeletal muscle.
Target Synonyms
BOP; CD8 beta opposite; CD8b opposite; Histone lysine N methyltransferase SMYD1; KMT3D; SET and MYND domain containing 1; SET and MYND domain-containing protein 1; SMYD1; SMYD1_HUMAN; Zinc finger MYND domain containing 18; ZMYND18; ZMYND22
Target Background
Predicted to enable histone-lysine N-methyltransferase activity. Involved in positive regulation of myoblast differentiation and positive regulation of myotube differentiation. Predicted to be located in cytoplasm. Predicted to be active in nucleus.
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