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The antibody against SNCAIP was raised in rabbit using the Recombinant Human Synphilin-1 protein (309-553AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against SNCAIP was raised in rabbit using the Recombinant Human Synphilin-1 protein (309-553AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human kidney tissue using SNCAIP Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human brain tissue using SNCAIP Antibody at dilution of 1:1002
Immunofluorescent analysis of Hela cells using SNCAIP Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-09989A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SNCAIP |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Synphilin-1 protein (309-553AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y6H5 |
Uniprot Id
Q9Y6H5
Target Species
Human
Target Name
SNCAIP
Target Full Name
Synphilin-1
Target Function
Isoform 2 inhibits the ubiquitin ligase activity of SIAH1 and inhibits proteasomal degradation of target proteins. Isoform 2 inhibits autoubiquitination and proteasomal degradation of SIAH1, and thereby increases cellular levels of SIAH. Isoform 2 modulates SNCA monoubiquitination by SIAH1.
Target Involvement
Parkinson disease (PARK)
Target Subcellular Location
Cytoplasm. Note=Detected in cytoplasmic inclusion bodies, together with SNCA.
Target Tissue Specificity
Detected in brain (at protein level). Widely expressed, with highest levels in brain, heart and placenta.
Target Synonyms
Alpha synuclein interacting protein; Alpha-synuclein-interacting protein; MGC39814; SNCAIP; SNCAP_HUMAN; Sph1; Synphilin-1; Synphilin1; Synuclein alpha interacting protein (synphilin); Synuclein alpha interacting protein; SYPH 1
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