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Rabbit anti-Human SNRNP70 Polyclonal Antibody

The antibody against SNRNP70 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 150-250 of human SNRNP70 (NP_003080.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-09613A

The antibody against SNRNP70 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 150-250 of human SNRNP70 (NP_003080.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

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Specifications


Cat.No ADA-09613A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSNRNP70
Target SynonymsRPU1; Snp1; U1AP; U170K; U1RNP; RNPU1Z; SNRP70; U1-70K; SNRNP70FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, Rat brain, HepG2, Jurkat, Mouse brain, U-251MGApplicationELISA, WB, IHC-P

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 150-250 of human SNRNP70 (NP_003080.2).Target SpeciesHuman
Immunogen SequenceEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKUniprot IDP08621
Background Information
  • Uniprot Id

    P08621

  • Target Species

    Human

  • Target Name

    SNRNP70

  • Target Full Name

    U1 small nuclear ribonucleoprotein 70 kDa

  • Target Function

    Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA.; Truncated isoforms that lack the RRM domain cannot bind U1-snRNA.; Truncated isoforms that lack the RRM domain cannot bind U1-snRNA.

  • Target Subcellular Location

    Nucleus speckle. Nucleus, nucleoplasm.

  • Target Research Area

    Epigenetics and Nuclear Signaling

  • Target Synonyms

    SNRNP70; RNPU1Z; RPU1; SNRP70; U1AP1U1 small nuclear ribonucleoprotein 70 kDa; U1 snRNP 70 kDa; U1-70K; snRNP70

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