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The antibody against SNRPD1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-119 of human SNRPD1 (NP_008869.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on IF/ICC, ELISA.
The antibody against SNRPD1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-119 of human SNRPD1 (NP_008869.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on IF/ICC, ELISA.
| Cat.No | ADA-02620A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SNRPD1 |
| Target Synonyms | SMD1; SNRPD; Sm-D1; HsT2456; SNRPD1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Application | ELISA, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-119 of human SNRPD1 (NP_008869.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MKLVRFLMKLSHETVTIELKNGTQVHGTITGVDVSMNTHLKAVKMTLKNREPVQLETLSIRGNNIRYFILPDSLPLDTLLVDVEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR | Uniprot ID | P62314 |
Uniprot Id
P62314
Target Species
Human
Target Name
SNRPD1
Target Full Name
Small nuclear ribonucleoprotein Sm D1
Target Function
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.
Target Subcellular Location
Cytoplasm, cytosol. Nucleus.
Target Protein Families
SnRNP core protein family
Target Synonyms
AA407109; AL023031; HsT2456; Sm D1; Sm-D autoantigen; Sm-D1; Small nuclear ribonucleoprotein D1 polypeptide; Small nuclear ribonucleoprotein Sm D1; SmD autoantigen; SMD1; SMD1_HUMAN; snRNP core protein D1; SNRPD; Snrpd1
Target Background
This gene encodes a small nuclear ribonucleoprotein that belongs to the SNRNP core protein family. The protein may act as a charged protein scaffold to promote SNRNP assembly or strengthen SNRNP-SNRNP interactions through nonspecific electrostatic contacts with RNA. Two transcript variants encoding different isoforms have been found for this gene.
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