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The antibody against SNX19 was raised in rabbit using the Human SNX19 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against SNX19 was raised in rabbit using the Human SNX19 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-51786A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SNX19 |
| Target Synonyms | SNX19 antibody; SNX19_HUMAN antibody; Sorting nexin 19 antibody; Sorting nexin-19 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human SNX19 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q92543 |
Uniprot Id
Q92543
Target Species
Human
Target Name
SNX19
Target Full Name
Sorting nexin-19
Target Function
Plays a role in intracellular vesicle trafficking and exocytosis. May play a role in maintaining insulin-containing dense core vesicles in pancreatic beta-cells and in preventing their degradation. May play a role in insulin secretion. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).
Target Subcellular Location
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
Target Protein Families
Sorting nexin family
Target Synonyms
SNX19; SNX19_HUMAN; Sorting nexin 19; Sorting nexin-19
Target Background
Islet antigen-2 (IA-2) is an autoantigen in type 1 diabetes and plays a role in insulin secretion. IA-2 is found in dense-core secretory vesicles and interacts with the product of this gene, a sorting nexin. In mouse pancreatic beta-cells, the encoded protein influenced insulin secretion by stabilizing the number of dense-core secretory vesicles.
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