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The antibody against SORBS3 was raised in rabbit using the Recombinant Human Vinexin protein (1-329AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against SORBS3 was raised in rabbit using the Recombinant Human Vinexin protein (1-329AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using SORBS3 Antibody at dilution of 1:1002
| Cat.No | ADC-23456A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SORBS3 |
| Target Synonyms | SORBS3 antibody; SCAM1 antibody; Vinexin antibody; SH3-containing adapter molecule 1 antibody; SCAM-1 antibody; Sorbin and SH3 domain-containing protein 3 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Vinexin protein (1-329AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O60504 |
Uniprot Id
O60504
Target Species
Human
Target Name
SORBS3
Target Full Name
Vinexin
Target Function
Vinexin alpha isoform promotes up-regulation of actin stress fiber formation. Vinexin beta isoform plays a role in cell spreading and enhances the activation of JNK/SAPK in response to EGF stimulation by using its third SH3 domain.
Target Subcellular Location
[Isoform Alpha]: Cell junction. Cytoplasm, cytoskeleton.; [Isoform Beta]: Cell junction. Nucleus. Cytoplasm, cytoskeleton.
Target Tissue Specificity
Both isoforms are expressed in different tissues like heart, placenta, brain, skeletal muscle and pancreas. Isoform beta is especially found in liver.
Target Synonyms
SORBS3; SCAM1; Vinexin; SH3-containing adapter molecule 1; SCAM-1; Sorbin and SH3 domain-containing protein 3
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