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The antibody against SP7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 333-376 of human SP7 (NP_001166938.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SP7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 333-376 of human SP7 (NP_001166938.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-12780A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SP7 |
| Target Synonyms | OSX; OI11; OI12; osterix; SP7 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, Mouse bone, U2OS | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 333-376 of human SP7 (NP_001166938.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | KRFTRSDELERHVRTHTREKKFTCLLCSKRFTRSDHLSKHQRTH | Uniprot ID | Q8TDD2 |
Uniprot Id
Q8TDD2
Target Species
Human
Target Name
SP7
Target Full Name
Transcription factor Sp7
Target Function
Transcriptional activator essential for osteoblast differentiation. Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences.
Target Involvement
Osteogenesis imperfecta 12 (OI12)
Target Subcellular Location
Nucleus.
Target Protein Families
Sp1 C2H2-type zinc-finger protein family
Target Tissue Specificity
Restricted to bone-derived cell.
Target Synonyms
MGC126598; Osterix; Osx; Sp 7; SP7; Sp7 transcription factor; SP7_HUMAN; Transcription factor Sp7; Zinc finger protein osterix
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