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The antibody against SPART was raised in rabbit using the Human SPG20 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against SPART was raised in rabbit using the Human SPG20 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
$600.00
| Cat.No | ADC-51761A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SPART |
| Target Synonyms | SPART antibody; KIAA0610 antibody; SPG20 antibody; TAHCCP1 antibody; Spartin antibody; Spastic paraplegia 20 protein antibody; Trans-activated by hepatitis C virus core protein 1 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human SPG20 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8N0X7 |
Uniprot Id
Q8N0X7
Target Species
Human
Target Name
SPART
Target Full Name
Spartin
Target Function
May be implicated in endosomal trafficking, or microtubule dynamics, or both. Participates in cytokinesis.
Target Involvement
Spastic paraplegia 20, autosomal recessive (SPG20)
Target Subcellular Location
Cytoplasm. Midbody.
Target Tissue Specificity
Ubiquitously expressed, with highest levels of expression detected in adipose tissue.
Target Synonyms
SPART; KIAA0610; SPG20; TAHCCP1; Spartin; Spastic paraplegia 20 protein; Trans-activated by hepatitis C virus core protein 1
Target Background
This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome).
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