Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against SPIB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-262 of human SPIB (NP_003112.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SPIB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-262 of human SPIB (NP_003112.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-09324A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SPIB |
| Target Synonyms | SPI-B; SPIB | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Raji | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-262 of human SPIB (NP_003112.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q01892 | Immunogen Sequence |
Uniprot Id
Q01892
Target Species
Human
Target Name
SPIB
Target Full Name
Transcription factor Spi-B
Target Function
Sequence specific transcriptional activator which binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. Promotes development of plasmacytoid dendritic cells (pDCs), also known as type 2 DC precursors (pre-DC2) or natural interferon (IFN)-producing cells. These cells have the capacity to produce large amounts of interferon and block viral replication. May be required for B-cell receptor (BCR) signaling, which is necessary for normal B-cell development and antigenic stimulation.
Target Subcellular Location
[Isoform 1]: Nucleus.; [Isoform 2]: Cytoplasm.
Target Protein Families
ETS family
Target Tissue Specificity
Expressed in plasmacytoid dendritic cells (pDCs) and B-cells, not expressed in T-cells or granulocytes. May also be enriched in stem cell populations of the liver.
Target Synonyms
SPI B; Spi B transcription factor; Spib; SPIB_HUMAN; Transcription factor Spi-B
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
