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The antibody against SPINK1 was raised in rabbit using the Recombinant protein of Human SPINK1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Affinity purified. This antibody has been validated on ELISA, WB.
The antibody against SPINK1 was raised in rabbit using the Recombinant protein of Human SPINK1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Affinity purified. This antibody has been validated on ELISA, WB.
$398.00
Western blot analysis of GST-SPINK1 recombinant protein using SPINK1 antibody.
| Cat.No | ADC-50911A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SPINK1 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant protein of Human SPINK1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P00995 |
Uniprot Id
P00995
Target Species
Human
Target Name
SPINK1
Target Full Name
Serine protease inhibitor Kazal-type 1
Target Function
Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin-catalyzed premature activation of zymogens.; In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production.
Target Involvement
Pancreatitis, hereditary (PCTT); Tropical calcific pancreatitis (TCP)
Target Subcellular Location
Secreted.
Target Research Area
Cell Biology
Target Synonyms
ISK1_HUMAN; Pancreatic secretory trypsin inhibitor; Pancreatic serine protease inhibitor Kazal; PCTT; PSTI; Serine protease inhibitor Kazal type 1; Serine protease inhibitor Kazal-type 1; Spink 3; SPINK1; Spink3; TaTI; TCP; Tumor associated trypsin inhibitor; Tumor-associated trypsin inhibitor
Target Background
The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis.
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