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The antibody against SPNS2 was raised in rabbit using the Recombinant Human Protein spinster homolog 2 protein (1-140AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
The antibody against SPNS2 was raised in rabbit using the Recombinant Human Protein spinster homolog 2 protein (1-140AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
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Immunofluorescent analysis of HepG2 cells using SPNS2 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
| Cat.No | ADC-15226A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SPNS2 |
| Target Synonyms | SPNS2 antibody; Protein spinster homolog 2 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Protein spinster homolog 2 protein (1-140AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IVW8 |
Uniprot Id
Q8IVW8
Target Species
Human
Target Name
SPNS2
Target Full Name
Sphingosine-1-phosphate transporter SPNS2
Target Function
Acts a a crucial lysosphingolipid sphingosine 1-phosphate (S1P) transporter involved in S1P secretion and function. S1P is a bioactive signaling molecule that regulates many physiological processes important for the development and for the immune system. Regulates levels of S1P and the S1P gradient that exists between the high circulating concentrations of S1P and low tissue levels that control lymphocyte trafficking.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein.
Target Protein Families
Major facilitator superfamily, Spinster (TC 2.A.1.49) family
Target Synonyms
SPNS2; Protein spinster homolog 2
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