Rabbit anti-Human SPON2 Polyclonal Antibody

The antibody against SPON2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 27-150 of human SPON2 (NP_036577.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-06778A

Number

Cat.No	ADA-06778A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	SPON2
Target Synonyms	DIL1; DIL-1; MINDIN; M-SPONDIN; SPON2	Form	Liquid
Species Reactivity	Human, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, Rat brain, HCT116	Application	ELISA, WB, IHC-P

Cat.No

ADA-06778A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

SPON2

Target Synonyms

DIL1; DIL-1; MINDIN; M-SPONDIN; SPON2

Form

Liquid

Species Reactivity

Human, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, Rat brain, HCT116

Application

ELISA, WB, IHC-P

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 27-150 of human SPON2 (NP_036577.1).	Target Species	Human
Immunogen Sequence	QPLGGESICSARAPAKYSITFTGKWSQTAFPKQYPLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGLRDFAERGEAWALMKEIEAAGEALQSVHAVFSAPAVPSGTGQTSAELEVQRRHSLVS	Uniprot ID	Q9BUD6

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 27-150 of human SPON2 (NP_036577.1).

Target Species

Human

Immunogen Sequence

QPLGGESICSARAPAKYSITFTGKWSQTAFPKQYPLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGLRDFAERGEAWALMKEIEAAGEALQSVHAVFSAPAVPSGTGQTSAELEVQRRHSLVS

Uniprot ID

Q9BUD6

Background Information

Uniprot Id

Q9BUD6
Target Species

Human
Target Name

SPON2
Target Full Name

Spondin-2
Target Function

Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens. Binds bacterial lipopolysaccharide (LPS).
Target Subcellular Location

Secreted, extracellular space, extracellular matrix.
Target Tissue Specificity

Expressed in normal lung tissue but not in lung carcinoma cell lines.
Target Synonyms

Differentially expressed in cancerous and non-cancerous lung cells 1; DIL 1; DIL-1; DIL1; DKFZp686G21139; FLJ16313; FLJ22401; FLJ34460; M spondin; Mindin; ORF Names: ; SPON 2; Spon2; SPON2_HUMAN; Spondin 2; Spondin 2 extracellular matrix protein; Spondin-2
Target Background

Predicted to enable antigen binding activity; lipopolysaccharide binding activity; and metal ion binding activity. Predicted to be involved in cell adhesion. Predicted to act upstream of or within several processes, including defense response to other organism; opsonization; and positive regulation of cytokine production. Located in extracellular exosome.

Rabbit anti-Human SPON2 Polyclonal Antibody

Specifications

Immunogen Information

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