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The antibody against SPRED2 was raised in rabbit using the Recombinant Human Sprouty-related, EVH1 domain-containing protein 2 protein (120-300AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against SPRED2 was raised in rabbit using the Recombinant Human Sprouty-related, EVH1 domain-containing protein 2 protein (120-300AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human testis tissue using SPRED2 Antibody at dilution of 1:100
| Cat.No | ADC-16759A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SPRED2 |
| Target Synonyms | SPRED2 antibody; Sprouty-related antibody; EVH1 domain-containing protein 2 antibody; Spred-2 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Sprouty-related, EVH1 domain-containing protein 2 protein (120-300AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q7Z698 |
Uniprot Id
Q7Z698
Target Species
Human
Target Name
SPRED2
Target Full Name
Sprouty-related, EVH1 domain-containing protein 2
Target Function
Negatively regulates Ras signaling pathways and downstream activation of MAP kinases. Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2. Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells.
Target Subcellular Location
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Target Tissue Specificity
Expressed in liver, skin, small intestine, salivary gland and prostate.
Target Synonyms
SPRED2; Sprouty-related; EVH1 domain-containing protein 2; Spred-2
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