Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against SPRY1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human SPRY1 (NP_005832.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SPRY1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human SPRY1 (NP_005832.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01379A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SPRY1 |
| Target Synonyms | hSPRY1; SPRY1 | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human SPRY1 (NP_005832.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MDPQNQHGSGSSLVVIQQPSLDSRQRLDYEREIQPTAILSLDQIKAIRGSNEYTEGPSVVKRPAPRTAPRQEKHERTHEIIPINVNNNYEHRHTSHLGHAVLPSNARGPILSRSTSTGSAASSGSNSSASSEQGLLGRSPPTRPVPGHRSERAIRTQPKQLIVDDLKGSL | Uniprot ID | O43609 |
Uniprot Id
O43609
Target Species
Human
Target Name
SPRY1
Target Full Name
Protein sprouty homolog 1
Target Function
Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2. Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells.
Target Subcellular Location
Cytoplasm. Membrane; Peripheral membrane protein. Note=Found in the cytoplasm in unstimulated cells but is translocated to the membrane ruffles in cells stimulated with EGF (epidermal growth factor).
Target Protein Families
Sprouty family
Target Synonyms
hSPRY1; Protein sprouty homolog 1; Sprouty 1; Sprouty homolog 1 antagonist of FGF signaling; Sprouty homolog 1; Spry-1; Spry1; SPY1_HUMAN
Target Background
Involved in negative regulation of fibroblast growth factor receptor signaling pathway. Located in Golgi apparatus; cytosol; and nucleoplasm.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
