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The antibody against SQLE was raised in rabbit using the Human SQLE as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against SQLE was raised in rabbit using the Human SQLE as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-47071A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SQLE |
| Target Synonyms | SQLE; ERG1; Squalene monooxygenase; Squalene epoxidase; SE | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human SQLE | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q14534 |
Uniprot Id
Q14534
Target Species
Human
Target Name
SQLE
Target Full Name
Squalene monooxygenase
Target Function
Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
Target Subcellular Location
Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.
Target Protein Families
Squalene monooxygenase family
Target Tissue Specificity
Detected in liver (at protein level).
Target Research Area
Cancer
Target Synonyms
SQLE; ERG1; Squalene monooxygenase; Squalene epoxidase; SE
Target Background
Enables FAD binding activity and squalene monooxygenase activity. Involved in lipid droplet formation; regulation of cell population proliferation; and sterol biosynthetic process. Located in intracellular membrane-bounded organelle. Is integral component of membrane.
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