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The antibody against SRGAP3 was raised in rabbit using the Human SRGAP3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against SRGAP3 was raised in rabbit using the Human SRGAP3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-51747A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SRGAP3 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Human SRGAP3 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O43295 |
Uniprot Id
O43295
Target Species
Human
Target Name
SRGAP3
Target Full Name
SLIT-ROBO Rho GTPase-activating protein 3
Target Function
GTPase-activating protein for RAC1 and perhaps Cdc42, but not for RhoA small GTPase. May attenuate RAC1 signaling in neurons.
Target Involvement
A chromosomal aberration involving SRGAP3 is found in a patient with severe idiopathic mental retardation (PubMed:12195014). Translocation t(X;3)(p11.2;p25) (PubMed:12195014).
Target Tissue Specificity
Highly expressed in adult and fetal brain. Expressed at low levels in kidney. Isoform 3 is expressed in the kidney but is absent in the brain.
Target Synonyms
ARHGAP 14; ARHGAP14; Gbi; ME GAP; MEGAP; Mental disorder associated GAP; Mental disorder-associated GAP; Rho GTPase activating protein 14; Rho GTPase-activating protein 14; SLIT ROBO Rho GTPase activating protein 3; SLIT-ROBO Rho GTPase-activating protein 3; srGAP 2; srGAP 3; srGAP2; srGAP3; SRGP 2; SRGP2; SRGP3_HUMAN; WAVE associated Rac GTPase activating protein; WAVE-associated Rac GTPase-activating protein; WRP
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