Rabbit anti-Human SRI Polyclonal Antibody

The antibody against SRI was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-198 of human SRI (NP_003121.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-13675A

Number

Cat.No	ADA-13675A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	SRI
Target Synonyms	SCN; V19; CP22; CP-22; RI	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa	Application	ELISA, WB

Cat.No

ADA-13675A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

SRI

Target Synonyms

SCN; V19; CP22; CP-22; RI

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-198 of human SRI (NP_003121.1).	Target Species	Human
Immunogen Sequence	MAYPGHPGAGGGYYPGGYGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVMSV	Uniprot ID	P30626

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-198 of human SRI (NP_003121.1).

Target Species

Human

Immunogen Sequence

MAYPGHPGAGGGYYPGGYGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVMSV

Uniprot ID

P30626

Background Information

Uniprot Id

P30626
Target Species

Human
Target Name

SRI
Target Full Name

Sorcin
Target Function

Calcium-binding protein that modulates excitation-contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels.
Target Subcellular Location

Cytoplasm. Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=Relocates to the sarcoplasmic reticulum membrane in response to elevated calcium levels.
Target Tissue Specificity

Detected in cardiac myocytes.
Target Research Area

Signal Transduction
Target Synonyms

22 kDa protein; Calcium binding protein amplified in mutlidrug resistant cells ; CP 22; CP-22; CP22; SCN; Sorcin (class 4 gene); Sorcin; SORCN_HUMAN; SRI; V19
Target Background

This gene encodes a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alternative splicing results in multiple transcript variants encoding distinct proteins. Multiple pseudogenes exist for this gene.

Rabbit anti-Human SRI Polyclonal Antibody

Specifications

Immunogen Information

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